SF 49ers @ Arizona Cardinals
The 49ers are favored by 6 1/2 in this one. The Cardinals will be competing with the Bears for that #1 draft pick this season. That means they are bad. In the past, they had an atrocious offense, but their defense at least kept them close. This year though, both sides of the ball are bad. They average just 13.7 points per game and give up 30...so that's what I think will happen in this one.
My Pick: 49ers 30, Cardinals 13